Khalid Alhazzani Selected Research

1-methyl-1H-indole-2-carboxylic acid (4- (1- (4- (4- acetylpiperazin- 1- yl)cyclohexyl)- 4- amino- 1H- pyrazolo(3,4- d)pyrimidin- 3- yl)- 2- methoxyphenyl)amide

1/2022

Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.

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Khalid Alhazzani Research Topics

Disease

14	Neoplasms (Cancer) 06/2022 - 11/2017
3	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 10/2018
2	Inflammation (Inflammations) 01/2022 - 01/2021
2	Breast Neoplasms (Breast Cancer) 12/2021 - 04/2018
2	Carcinogenesis 12/2021 - 01/2020
2	Autistic Disorder (Autism) 02/2021 - 01/2021
2	Ovarian Neoplasms (Ovarian Cancer) 12/2019 - 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 06/2022
1	Melanoma (Melanoma, Malignant) 02/2022
1	Otitis 01/2022
1	Cardiotoxicity 09/2021
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 06/2021
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Carcinoma (Carcinomatosis) 11/2020
1	Multiple Myeloma 01/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Acute Lung Injury 01/2019
1	Vascular System Injuries 01/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Pathologic Processes 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2019

Drug/Important Bio-Agent (IBA)

2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 06/2022 - 11/2017
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 02/2022 - 12/2021
2	Metformin (Glucophage)FDA LinkGeneric 02/2022 - 12/2021
2	Interleukin-17 (Interleukin 17)IBA 01/2022 - 02/2021
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2022 - 11/2017
2	Pharmaceutical PreparationsIBA 12/2021 - 01/2019
2	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2021 - 12/2019
2	Cisplatin (Platino)FDA LinkGeneric 06/2021 - 12/2019
2	PlatinumIBA 12/2019 - 01/2019
2	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2019 - 11/2017
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2019
2	Paclitaxel (Taxol)FDA LinkGeneric 04/2018 - 11/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2022
1	Immune Checkpoint InhibitorsIBA 02/2022
1	SenotherapeuticsIBA 01/2022
1	Imiquimod (Aldara)FDA LinkGeneric 01/2022
1	CytokinesIBA 01/2022
1	Angiogenesis InhibitorsIBA 01/2022
1	1-methyl-1H-indole-2-carboxylic acid (4- (1- (4- (4- acetylpiperazin- 1- yl)cyclohexyl)- 4- amino- 1H- pyrazolo(3,4- d)pyrimidin- 3- yl)- 2- methoxyphenyl)amideIBA 01/2022
1	p38 Mitogen-Activated Protein KinasesIBA 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	anthraceneIBA 12/2021
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 12/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2021
1	Valsartan (Vals)FDA Link 09/2021
1	statticIBA 06/2021
1	Interleukin-9 (Interleukin 9)IBA 02/2021
1	Therapeutic UsesIBA 02/2021
1	5-aminoisoquinolinoneIBA 02/2021
1	Interleukin-10 (Interleukin 10)IBA 02/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2021
1	PlasticizersIBA 01/2021
1	phthalic acid (phthalate)IBA 01/2021
1	Diethylhexyl Phthalate (DEHP)IBA 01/2021
1	Lipid NanoparticlesIBA 11/2020
1	Proteins (Proteins, Gene)FDA Link 11/2020
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2020
1	brigatinibIBA 11/2020
1	Antineoplastic Agents (Antineoplastics)IBA 11/2020
1	Cell Cycle ProteinsIBA 01/2020
1	Oncogene Proteins (Oncogene Protein)IBA 01/2020
1	Aurora Kinase BIBA 01/2020
1	EndopeptidasesIBA 01/2019
1	ZincIBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019
1	carfilzomibIBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Proteasome InhibitorsIBA 01/2019
1	apremilastIBA 01/2019
1	Peroxidase (Myeloperoxidase)IBA 01/2019
1	taxaneIBA 01/2019
1	ProdrugsIBA 01/2019
1	nutlin 3IBA 10/2018
1	Mitogen-Activated Protein KinasesIBA 11/2017
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2017
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 11/2017
1	Mucin-1 (CA 15-3 Antigen)IBA 11/2017

Therapy/Procedure

5	Therapeutics 06/2022 - 01/2019
3	Drug Therapy (Chemotherapy) 06/2022 - 01/2019